MyMD Pharmaceuticals Enrolls First Client in Stage 2 Scientific Test of MYMD-1 as a Treatment for Delaying Aging and Increasing Healthy Life-span
MyMD Pharmaceuticals Enrolls First Client in Stage 2 Scientific Test of MYMD-1 as a Treatment for Delaying Aging and Increasing Healthy Life-span

MyMD Pharmaceuticals Enrolls First Client in Stage 2 Scientific Test of MYMD-1 as a Treatment for Delaying Aging and Increasing Healthy Life-span

MyMD Pharmaceuticals, Inc. MyMD Pharmaceuticals (” MyMD” or “the Company”), a medical phase pharmaceutical firm committed to prolonging healthy and balanced life-span, today revealed that the first patient has actually been enrolled in the Company’s Phase 2 scientific trial of lead prospect MYMD-1, a dental immune regulator drug, as a therapy for postponing aging and also expanding healthy life expectancy.

The primary endpoint for the Phase 2 double-blind, placebo-controlled professional trial is to accomplish a reduction in the circulating levels of (TNF-α), lump death element receptor I (TNFRI) and IL-6. TNF-α as well as IL-6 are the healthy proteins in the body that trigger inflammation and assist turn on the process of aging. The additional measures of the test will certainly be the safety, tolerability, as well as pharmacokinetics in this populace of individuals.

” In a Phase 1 clinical test of MYMD-1, we demonstrated the medication’s statistically considerable effectiveness in reducing degrees of TNF-α, a key player in triggering pathological aging, in the blood. The FDA has approved TNF-α reduction as the primary endpoint for our Stage 2 research, which we believe settings us well for a successful Phase 2 end result,” claimed Chris Chapman, M.D., Head Of State, Director and Chief Medical Policeman of MyMD. “The initiation of patient registration in this study breakthroughs our mission to slow down the aging procedure, prevent loss of muscle mass tissue in aging, limit frailty, as well as extend healthy life expectancy.”

MyMD has actually mentioned that there are no FDA-approved medications for treating aging conditions and also extending healthy life expectancy humans, a market anticipated to be at least $600 billion by 20251 according to a major investment bank. TNF-α blockers are one of the most proposed medications by earnings, a global market of approximately $40 billion each year,2 and, according to Nature Aging journal,3 a slowdown in maturing that would boost life expectancy by one year deserves $38 trillion as well as by 10 years deserves $367 trillion.

In addition to aging, MYMD-1’s unique action in controling the immune system as well as dealing with chronic inflammation is being developed for the treatment of autoimmune illness, including rheumatoid joint inflammation (RA), multiple sclerosis (MS), diabetes, and also inflammatory bowel disease.

” We intend to start creating methods for a Phase 2 pilot research study of MYMD-1 for rheumatoid joint inflammation early this year,” Dr. Chapman noted. “The rising occurrence of rheumatoid arthritis as well as various other autoimmune and also inflammatory conditions are driving need for TNF preventions like MYMD-1, as well as our team believe our orally administered medication with extremely low toxicity would be disruptive to the $60 billion market for RA if approved by the FDA for this sign.”

Rheumatoid arthritis affects about 40 million individuals globally.4.

Concerning MYMD-1.

Initially developed for autoimmune conditions, MYMD-1’s primary objective is to reduce the aging process, prevent sarcopenia as well as frailty, and also expand healthy lifespan. Due to the fact that it can cross the blood-brain obstacle and get to the main nervous system (CNS), MYMD-1 is likewise placed to be a possible treatment for brain-related conditions. Its system of activity as well as efficiency in diseases consisting of numerous sclerosis (MS) and also thyroiditis have been researched via collaborations with a number of academic institutions. MYMD-1 is also showing promise in pre-clinical researches as a prospective therapy for post- COVID-19 difficulties and also as an anti-fibrotic as well as anti-proliferation therapeutic.

MYMD-1 has actually shown effectiveness in pre-clinical studies in regulating the immune system by doing as a careful inhibitor of tumor death factor-alpha (TNF-α), a vehicle driver of persistent inflammation. Unlike various other therapies, MYMD-1 has been displayed in these pre-clinical researches to precisely block TNF-α when it comes to be overactivated in autoimmune conditions as well as cytokine tornados, but not block it from doing its typical task of being a first -responder to any type of regular type of moderate infection. MYMD-1’s convenience of dental dosing is one more differentiator contrasted to currently readily available TNF-α blockers, all of which call for shipment by injection or infusion. No approved TNF prevention has actually ever been dosed by mouth. On top of that, the medicine is not immunosuppressive and has actually not been shown to trigger the significant adverse effects typical with traditional therapies that deal with inflammation.

About MyMD Pharmaceuticals, Inc

. MyMD Pharmaceuticals, Inc. (Nasdaq: MYMD), a clinical phase pharmaceutical business committed to expanding healthy life expectancy, is concentrated on establishing 2 novel restorative platforms that treat the causes of illness instead of just resolving the symptoms. MYMD-1 is a medicine platform based on a professional phase tiny molecule that regulates the body immune system to control TNF-α, which drives chronic swelling, as well as various other pro-inflammatory cell signaling cytokines. MYMD-1 is being established to postpone aging, boost longevity, and treat autoimmune conditions as well as COVID-19- connected anxiety. The Company’s 2nd medicine system, Supera-CBD, is being developed to deal with persistent discomfort, dependency and also epilepsy. Supera-CBD is an unique artificial derivative of cannabidiol (CBD) and is being created to attend to and also improve upon the rapidly growing CBD market, that includes both FDA authorized medications and also CBD items not presently controlled as drugs. To find out more, check out

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